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London Lab

 
 
 
 
 
 
 
 

Jernej Ule, 'Jernej' is pronounced as Yernay. I obtained my BSc in Molecular Biology from University of Ljubljana, Slovenia, in 1999, and PhD and short postdoc with Bob Darnell at the Rockefeller University, New York, during 2000-2006. I started my research group at the MRC Laboratory of Molecular Biology in Cambridge in July 2006, in April 2013 we moved to the Queen Square UCL Institute of Neurology in London, in August 2016 we were seconded for 6 years to The Francis Crick Institute. In September 2022 we moved to UK Dementia Research Institute at King's, where I took the position of UK DRI Centre Director, with the goal to jointly progress in our understanding of the molecular pathogenesis of Amyotrophic Lateral Sclerosis (ALS) and developing new therapeutic strategies. A satellite team of 3 people remains in the Crick until 2024 to complete the work on a Wellcome Trust grant, and a satellite team at the Institute of Chemistry in Ljubljana focuses on bioinformatics and new methods for studies of RNP condensates (funded by ERC advanced grant since 2020). I am an EMBO fellow and a member of London RNA club, I like to review papers and grants, and I served on WT grant reviewing board and EMBO conference reviewing committee.

Martina Hallegger, Postdoc since October 2014 (MNDA non-clinical fellow in 2016-19). Studies ribonucleoprotein complexes in motor neuron disease.

Cristina Militti, Postdoc since October 2014 (EMBO postdoctoral fellow in 2015-16). Studies mRNA structures and their role in RNP assembly and function.

Flora Lee, Postdoc studying the neuronal functions of mRNA structures, was PhD student during 2016-2019 (Wellcome Trust UCL neuroscience programme).

Julian Zagalak, Postdoc since January 2016 (funded by SNF fellowship in 2016-17). Studies combinatorial control of pre-mRNA processing.

Rupert Faraway, Postdoc studying the assembly of RNP condensates, was PhD student 2017-2020 (UCL MRC LIfe and Biomedical Science DTP PhD).

Patrick Toolan-Kerr, Postdoc studying the effects of RNA methylation on RNP assembly, was PhD student 2017-2020 (UCL Wolfson PhD).

Miha Modic, Postdoc since Dec 2017 (Henry Wellcome postdoctoral fellow), studies the functions of RNPs in stem cell differentiation.

Wei Jia Zhang, PhD student since 2018, (UCL Wolfson PhD programme), studies RNP dynamics in neurodegeneration, currently on one-year clinical placement.

Oscar Wilkins, PhD student since Oct 2019 (Wellcome Trust UCL neuroscience PhD). Studies translational control by neuronal RNA binding proteins.

Llywelyn Griffith, joint AstraZeneca/Crick postdoc since Oct 2019, studies treatments targeting aberrant splicing in cancer.

Joyita Mukherjee, Postdoc since Feb 2020 (EMBO postdoctoral fellowship in 2021-23). Studies the dynamics of neuronal RNP condensates.

Hanzhong Bai, PhD student since Oct 2020 (LIDO programme and Boehringer Ingelheim fellowship). Studies RNA-RNA contacts in neurons.

Neve Costello Heaven, PhD student since Oct 2021 (UCL Wolfson-Eisai programme), studies the role of RNA condensates in neurodegeneration.

Holly Digby, Research assistant since February 2020, works mainly with Rupert.

Ira A. Iosub, Postdoc since 2020 on computational studies of RNA structures.

Karen Davey, Research assistant since 2022, works on RNA biochemistry and cell biology.

Owen Gwydion James, Gwyd is a postdoc since Sept 2022, studies the roles of aberrant protein-RNA complexes in ALS to develop new therapies.

Anna Muchiewicz, BSc student on a one-year extra-mural placement (2022-23) to work with Karen Davey and Gwyd.

 
 
 
 
 
 
 

Ljubljana Lab

Aniela Skrzypczyk, postdoc since April 2022, studies mechanisms of RNA condensates in neuronal differentiation.

Klara Kuret, MSc student since November 2019 and started PhD in 2020, works on computational studies of nuclear RNP condensates.

Tajda Klobučar, PhD student since 2020, studies protein-RNA and RNA-RNA interactions that assemble nuclear RNP condensates, mentored by Miha Modic.

Urška Janjoš, Research assistant since December 2020 and PhD student since 2021, studies the functions of nuclear RNP condensates.

Anja Trupej, MSc student since 2020, and then starting PhD in October 2022, works on proximity-based studies of RNP condensates.

Žiga Vičič, Research assistant since October 2021, works on iCLIP, ribosome profiling and molecular biology.

Maksimiljan Adamek, PhD student since 2022, works on biochemistry and structural studies of protein-RNA complexes.

Jure Rebselj, MSc student since Sept 2022, focusing on computational biology.

 
 

Affiliated

Charlotte Capitanchik, was PhD student working between Nick Luscombe and Ule labs (2017-2022), now on a one-year fellowship in Nick's Okinawa's lab.

Reem Abouward, PhD student working between Gianpietro Schiavo and Ule labs since October 2020 as part of the Wellcome Trust UCL neuroscience PhD programme. Studies the role of RNA transport in ALS.

Anob M. Chakrabarty, working between Nick Luscombe and Ule groups, PhD student 2016-2020, now postdoc working on computation of mRNA structures.

Julie Qiaojin Lin, Sir Henry Wellcome postdoctoral Fellow affiliated to the groups of Giovanna Malucci and Clemens Kaminski, in addition to Ule lab

Grega Gimpelj, PhD student at Medical Faculty in Ljubljana, performs part of his PhD in the Ljubljana lab.

 
 
 
 
 
 
 
 
 
 
 
 
 
 

Past Lab Members

James Tollervey, PhD student during October 2006 - April 2010. Now Associate Director of R&D at LGC Biosearch Technologies.

Zhen Wang, PhD student during October 2007 - September 2010. Now senior scientist at Depixius, Paris.

Melis Kayikci, PhD student during October 2008 - September 2011. Now bioinformatician at Genomics England.

Michael Briese, postdoc during December 2007 - March 2012. Now lecturer at the University of Wurzburg.

Nicholas McGlincy, joint postdoc with the group of Michael Hastings during November 2008 – August 2012, now Scientist III at Zymergen.

Julian König, postdoc during November 2008 - October 2013, funded by HFSP Postdoctoral Fellowship. In 2014 started his research team in Mainz.

Yoichiro Sugimoto, PhD student during October 2010 - July 2014, funded by the Nakajima Foundation. In 2022 started his research team in Berlin.

Chris Sibley, postdoc during August 2011-October 2015, in 2020 started his research team at the Edinburgh University.

Jan Attig, PhD student during October 2011-April 2015, funded by Boehringer Ingelheim Scholarship. Now senior scientist at Roche, Basel.

Ina Huppertz, PhD student during October 2012-September 2015, funded by Marie Sklodowska Curie ITN. In 2022 started her research team in Cologne.

Claire Hall, PhD student during Sept 2013 - Sept 2016, was funded by UCL Grand Challenge programme, then proceeded to medical school.

Nejc Haberman, PhD student during 2013 - 2017 on computation of protein-RNA interactions, now postdoc at MRC CSC in London.

Lilach Soreq, Postdoctoral fellow during August 2013 - November 2016, now senior bioinformatician in Israel.

Warren Emmett, Postdoctoral fellow during March 2016 - February 2018, now Bioinformatics Analyst at Inivata Limited in Cambridge, UK.

Igor Ruiz de los Mozos, Postdoctoral fellow from Nov 2014-Sept 2019, now senior bioinformatician at Spain genomics institute.

Andrea Elser, PhD student during 2016-2019 as part of the BBSRC LIDo Doctoral Training Programme. Now postdoc at Astra Zeneca.

Lorea Blazquez, postdoc during 2014-2018 (Marie Skłodowska-Curie fellowship). In 2021 started her research team at Biodonostia Health Research Institute, Spain.

Paulo Gameiro, Postdoctoral researcher 2016-2021 (Marie Skłodowska-Curie fellowship). In 2022 started his research team at the University of Coimbra, Portugal.

 
 
 
 
 
 
 
 
 

Past Lab Members (<3 years)

Iris Kramberger, visiting student during August-September 2010, then a PhD student in Oxford.

Matteo Cereda, visiting student for 9 months in 2010 and 2011, now team leader in Milan.

Dalia Daujotyte, short-term postdoc for five months in 2010 to study Staufen 2 protein using iCLIP. Now at Illumina.

Tina Lence, visiting student during March-August 2011. Now postdoc at IMB Mainz.

Josh Witten, short-term postdoc during January 2010 – June 2012. Now runs The Finch & Pea Group, Ltd - a life sciences and communication consulting firm.

Katherine Godin, short-term postdoc during October 2011 - September 2012. Now NMR Senior Scientist at Beryllium

Deepak Barnabas, 3-month visiting student November 2012 - January 2013.

Peter Juvan, visiting scientist December 2012 - February 2013.

Mojca Tajnik, visiting student, staying from March 2011 - March 2012, and March 2013-June 2013, funded by EMBO Short-term scholarship.

Laura Easton, research assistant during October 2011 - March 2013.

Andrea D'Ambrogio, postdoc during January 2013-August 2014. Now Senior Scientist at Horizon Discovery.

Rubika Balendra, PhD rotation student in 2015, funded by UCL Wolfson programme.

Liza Malong, PhD rotation student during March-May 2015 as part of the neuroscience PhD programme.

Aarti Singh, MSc student during March-September 2014, then research assistant during October 2014-September 2015. Now PhD student at UCL.

Alexandra Zirra, MSc student during March-September 2014, then research assistant during October 2014-September 2015. Now a PhD student at KCL.

Rehan Hussain, MSc student during March-September 2016. Worked with Cristina Militti.

Isabel Weisheit, visiting student from Ludwig Maximilans University of Munich, visited from June-November 2016 to work with Martina Halleger.

Gregor Rot visited our group and collaborated on bioinformatic projects to study the regulation of 3' end processing .

Frederique Rau, Postdoctoral fellow with Rickie Patani, who was hosted in our lab for a year, now young researcher in France.

Eleni Anastasakou, Lena was an MRes student during Oct 2016 - Sept 2017. Studied the long-range mRNA structures, together with Cristina.

Violeta Castelo Szekely, one-year visiting student Oct 2016 - Sept 2017 from the University of Lausanne, funded by the NCCR Doctoral Mobility grant.

Pablo Izquierdo Garrudo, PhD rotation student in spring 2017 as part of the Wellcome Trust UCL neuroscience PhD programme.

Katja Egli, Research assistant since October 2016, works mainly with Martina and Flora.

Liam Kempthorne, PhD rotation student in spring 2018, UCL Wolfson programme.

Michael Palo, summer student from University of Madison, July-August 2018, now PhD student at Stanford.

Jan Brancewicz, summer student from Warsaw University, July-August 2018.

Edwin Jarratt Barnham, summer student from University of Cambridge, July-August 2019

Adam Sheriff, summer student from King’s College London, July-August 2019

Hallie Hanson, summer student from University of Wisconsin-Madison, July-August 2019

Emma Groblewski, summer student from University of Wisconsin-Madison, July-August 2019

Federica Capraro, MSc student and then research assisitant during January 2018 - August 2019. Now a LIDo PhD student in London.

Christoph Sadee, Research assistant Oct 2016 - Nov 2018, working on a new magnetic rack among others.

Mariša Cvitanič, MSc student during July 2019-March 2020, worked with Miha Modic on RNA regulation in stem cells.

Yiling Li, MRes student during October 2019 - September 2020, continued to PhD studies in Magdalena Gotz's lab at the LMU Munich.

Velentza-Almpani Angeliki, MSc student during Jan-Sept 2020.

Aram Amalietti, Data Analyst during February 2019 - July 2021, software development and computational analyses of CLIP data.

Miha Sovrovič, Research assistant during December 2020 - September 2021, worked on ribosome profiling and genome editing.

Nina Lenaršič, Summer student in 2021, worked with Urška Janjoš.

Špela Barbič, Summer student in 2021, worked with Miha Milek.

Parth Patel, MSc student in Oct 2018-Sept 2019, and research assistant during Jan-Sept 2020 working on splicing modulation.

Lea Knez, Erasmus visiting student during Sept-Nov 2021, worked with Rupert Faraway

Zuzana Koskova, Erasmus visiting student during Sept-Dec 2021, worked with Martina Hallegger.

Stacy Steinberg, was Marie-Currie International postdoctoral fellow working between Su Guo lab at UCSF and Ule lab on the protein Rbm12a.

Miha Milek, Senior postdoctoral researcher during Jan 2020 - Mar 2022, who helped establish the Ljubljana team and worked on Staufen RNP assembly.

Nuša Avguštinčič, BSc student visiting Ljubljana team in winter 2022.

Marc Jones, Postdoc working between Nick Luscombe and Ule labs during 2020-2022 on computational RNA biology.

Mahmoud-Reza Sina Rafiee, Postdoctoral fellow between Nicholas Luscombe and Ule teams during 2018-2022, developed new proteomic methods.

Katarina Lenarčič, MSc student from 2021-2022.

Perlina Desai, rotating PhD student with UCL-Birkbeck DTP programme in 2021.

Maria Pisliakova, visiting student during July 2021-August 2022, worked with Oscar Wilkins.