London Lab

Jernej Ule
Martina Hallegger
Cristina Militti
Flora Lee
Julian Zagalak
Paulo Gameiro
Rupert Faraway
Patrick Toolan-Kerr
Miha Modic
Wei Jia Zhang
Oscar Wilkins
Llywelyn Griffith
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Jernej Ule, 'Jernej' is pronounced as Yernay (ending like RNA). I obtained my BSc in Molecular Biology from University of Ljubljana, Slovenia, in 1999, and PhD with Bob Darnell at the Rockefeller University, New York, in 2004, where I continued for a two-year postdoc. I started my research group at the MRC Laboratory of Molecular Biology in Cambridge in July 2006, and in April 2013 we have moved to the Queen Square UCL Institute of Neurology. In August 2016, my group has been seconded to The Francis Crick Institute in London. I also act as a reviewer, serve on the editorial board of Genome Biology, am the EMBO fellow and serve on the EMBO Course Committee (2018-2021), and a member of Wellcome Expert Review Group, Molecular Basis of Cell Function (2018-2022).

Martina Hallegger, Postdoctoral researcher since October 2014 (funded by MNDA non-clinical fellowship in 2016-19). Studies ribonucleoprotein complexes in motor neuron disease.

Cristina Militti, Postdoctoral researcher since October 2014 (funded by EMBO postdoctoral fellowship in 2015-16). Studies mRNA structures and their role in RNP assembly and function.

Flora Lee, PhD student 2016-2019 as part of the Wellcome Trust UCL neuroscience PhD programme, now a postdoctoral researcher. Studies the neuronal functions of mRNA structures.

Julian Zagalak, Postdoctoral researcher since January 2016 (funded by SNF fellowship in 2016-17). Studies combinatorial control of pre-mRNA processing.

Paulo Gameiro, Postdoctoral researcher since September 2016 (Marie Skłodowska-Curie fellowship 2016-18). Studies the metabolic control of protein-RNA interactions.

Rupert Faraway, PhD student as part of the UCL MRC LIfe and Biomedical Science DTP PhD programme, studies the roles of RNPs in neuronal differentiation. Also co-supervises the translational project together with Lorea Blazquez.

Patrick Toolan-Kerr, PhD student as part of the UCL Wolfson PhD programme, studies the way that RNA methylation affects RNP assembly.

Miha Modic, Postdoctoral researcher since December 2017, now Henry Wellcome postdoctoral fellow, additionally affiliated with Kathyn Lilley and Magdalena Zernicka-Gotz groups. Studies the functions of RNPs in stem cell differentiation.

Wei Jia Zhang, PhD student as part of the UCL Wolfson PhD programme, studies RNP dynamics in motor neurons and in ALS.

Oscar Wilkins, PhD student since October 2019 as part of the Wellcome Trust UCL neuroscience PhD programme. Studies translational control by neuronal RNA binding proteins.

Llywelyn Griffith, since October 2019, joint AstraZeneca/Crick postdoctoral fellow performing part of his work in my lab. Studies treatments targeting aberrant splicing in cancer.

Hanzhong Bai, MSc student during March 2020 - November 2020, working with Flora and Llywelyn on analyses of CLIP data.


Ljubljana Lab

Aram Amalietti
Miha Milek
Klara Kuret
Tajda Klobučar
Katarina Lenarčič
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Aram Amalietti, Data Analyst since February 2019, software development and computational analyses of CLIP data.

Miha Milek, Postdoctoral researcher since January 2020, coordinates the experimental RNA research of the Ljubljana team.
Klara Kuret, MSc student since November 2019, and started PhD with Miha Milek in October 2020, working mainly on computational aspects of protein-RNA interactions.

Tajda Klobučar, Started PhD with Miha Modic in October 2020, working on protein-RNA interactions.

Anja Trupej, MSc student since April 2019, works with Klara and Miha Milek on iCLIP and related experiments.

Katarina Lenarčič, MSc student since July 2019, works with Miha Milek on molecular biology experiments.



Reem Abouward
Parth Patel
Stacy Steinberg
Charlotte Capitanchik
Anob Chakrabarty
Mahmoud-Reza Rafiee
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Reem Abouward, PhD student working between Gianpietro Schiavo and Ule labs since October 2020 as part of the Wellcome Trust UCL neuroscience PhD programme. Studies the role of RNA transport in ALS.

Parth Patel, MSc student in Oct 2018-Sept 2019, and research assistant since January 2020 on a Crick-LifeArc translational project.

Holly Digby, research assistant since February 2020 on a Crick-LifeArc translational project.

Stacy Steinberg, Marie-Currie International fellow, working between Su Guo lab at UCSF and Ule lab.

Charlotte Capitanchik, a PhD student working jointly with the group of Nick Luscombe as part of the Crick PhD programme, performs computational analyses of RNP assembly.

Anob M. Chakrabarty, joint PhD student with Nicholas Luscombe 2016-2019, now a postdoctoral fellow.. Computational studies of mRNA structures.

Mahmoud-Reza Sina Rafiee, Postdoctoral fellow with Nicholas Luscombe, who uses proteomics to study RNPs.


Past Lab Members

James Tollervey
James Tollervey
Zhen Wang
Melis Kayikci
Michael Briese
Nicholas McGlincy
Julian Konig
Yoichiro Sugimoto
Chris Sibley
Jan Attig
Ina Huppertz
Claire Hall
Nejc Haberman
Lilach Soreq
Warren Emmett
Igor Ruiz de los Mozos
Andrea Elser
Andrea Elser
Lorea Blazquez
Lorea Blazquez
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James Tollervey, PhD student during October 2006 - April 2010, then postdoc till December 2010. Worked on regulation alternative splicing in age-related neurologic disorders. Now scientist at Aelan Cell Technologies, San Francisco.

Zhen Wang, PhD student during October 2007 - September 2010, then postdoc till September 2011. Studied how TIA proteins regulate RNA splicing and 3' end processing. Now senior scientist at Depixius, Paris.

Melis Kayikci, PhD student during October 2008 - September 2011. Studied the positional principles, or 'RNA maps', which guide the regulatory activity of RNA-binding proteins. Now bioinformatician at Genomics England.

Michael Briese, postdoc during December 2007 - March 2012. Studied how CELF4 protein regulates translation in mouse brain. Now postdoctoral fellow at University of Wurzburg.

Nicholas McGlincy, joint postdoc with the group of Michael Hastings during November 2008 – August 2012. Studied the role of alternative splicing in circadian rhythms. Now postdoc at the University of California, Berkley.

Julian König, postdoc suring November 2008 - October 2013. Studied the function of hnRNP C protein in the regulation of alternative splicing. Was funded by HFSP Postdoctoral Fellowship. Now group leader at the Institute of Molecular Biology in Mainz.

Yoichiro Sugimoto, PhD student during October 2010 - July 2014, and then postdoc during May-September 2016. Studied the function of in vivo RNA structures. His PhD was funded by the Nakajima Foundation Scholarship.

Chris Sibley, postdoc during August 2011-October 2015. Studied intronic splicing regulatory elements in neuronal genes. Now group leader at the Imperial College Londony.

Jan Attig, PhD student during October 2011-April 2015, then postdoc till September 2015. Studies the coordinated control of mRNA life cycle. Was funded by Boehringer Ingelheim Scholarship. Now postdoc at the Crick Institute.

Ina Huppertz, PhD student during October 2012-September 2015. Studies the regulation of pre-mRNA processing. Was funded by Marie Curie International Training Network. Now postdoc at EMBL.

Claire Hall, PhD student during Sept 2013 - Sept 2016. Studied RNA regulatory networks in motor neuron disease, and was funded by UCL Grand Challenge programme. Now at medical school.

Nejc Haberman, PhD student during August 2013 - June 2017. Performed computational studies of protein-RNA interactions, and was by UCL Grand Challenge programme. Now postdoc at MRC CSC in London, UK.

Lilach Soreq, Postdoctoral fellow during August 2013 - November 2016, now an independent Research Associate funded by the Alzheimer Society UK. Studies RNA regulatory networks in neurodegenerative diseases.

Warren Emmett, Postdoctoral fellow during March 2016 - February 2018. Coordinated computational studies of non-canonical splicing. Now Bioinformatics Analyst at Inivata Limited in Cambridge, UK.

Igor Ruiz de los Mozos, Postdoctoral fellow from Nov 2014-Sept 2019, studying the network mechanisms of RNA regulation and is transitioning to his next research position in Spain.

Andrea Elser, PhD student during 2016-2019 as part of the BBSRC LIDo Doctoral Training Programme. Studied the function of recursive splice sites in neurons.

Lorea Blazquez, postdoc since 2014, studying regulation of recursive splicing (initially funded by Marie Skłodowska-Curie postdoctoral fellowship), and since 2018, co-supervises a Crick-LifeArc translational project. In August 2020 started her own research group as 'Ramon y Cajal' and 'Ikerbasque' researcher in the Neurosciences Department of Biodonostia Health Research Institute.


Past Lab Members (<3 years)

Iris Kramberger
Matteo Cereda
Dalia Daujotyte
Tina Lence
Josh Witten
Katherine Godin
Deepak Barnabas
Peter Juvan
Mojca Tajnik
Laura Easton
Andrea D'Ambrogio
Rubika Balendra
Liza Malong
Aarti Singh
Alexandra Zirra
Rehan Hussain
Isabel Weisheit
Gregor Rot
Frederique Rau
Violeta Castelo Szekely
Pablo Izquierdo Garrudo
Katja Egli
Liam Kempthorne
Christoph Sadee
Mariša Cvitanič
Yiling Li
Velentza-Almpani Angeliki
Hanzhong Bai
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Iris Kramberger, visiting student during August-September 2010. Now a PhD student in Oxford.

Matteo Cereda, a visiting student for 9 months in 2010 and 2011, working on a computational approach to define RNA splicing maps. Now a group leader at IIGM, Turin.

Dalia Daujotyte, short-term postdoc for five months in 2010 to study Staufen 2 protein using iCLIP. Now Chief Commercial Officer at the Lexogen company in Vienna.

Tina Lence, visiting student during March-August 2011. Now postdoc at IMB Mainz.

Josh Witten, short-term postdoc during January 2010 – June 2012. Now runs The Finch & Pea Group, Ltd - a life sciences and communication consulting firm.

Katherine Godin, short-term postdoc during October 2011 - September 2012. Now NMR Senior Scientist at Beryllium

Deepak Barnabas, 3-month visiting student November 2012 - January 2013.

Peter Juvan, visiting scientist December 2012 - February 2013.

Mojca Tajnik, visiting student, staying from March 2011 - March 2012, and March 2013-June 2013. Mojca was funded by EMBO Short-term scholarship.

Laura Easton, research assistant during October 2011 - March 2013.

Andrea D'Ambrogio, postdoc during January 2013-August 2014. Now Senior Scientist at Horizon Discovery.

Rubika Balendra, PhD rotation student in 2015, funded by UCL Wolfson programme.

Liza Malong, PhD rotation student during March-May 2015 as part of the neuroscience PhD programme.

Aarti Singh, MSc student during March-September 2014, then research assistant during October 2014-September 2015. Now PhD student at UCL.

Alexandra Zirra, MSc student during March-September 2014, then research assistant during October 2014-September 2015. Now a PhD student at KCL.

Rehan Hussain, MSc student during March-September 2016. Worked with Cristina Militti.

Isabel Weisheit, visiting student from Ludwig Maximilans University of Munich, visited from June-November 2016 to work with Martina Halleger.

Gregor Rot visited our group and collaborated on bioinformatic projects to study the regulation of 3' end processing .

Frederique Rau, Postdoctoral fellow with Rickie Patani, who was hosted in our lab for a year.

Eleni Anastasakou, Lena was an MRes student during Oct 2016 - Sept 2017. Studied the long-range mRNA structures, together with Cristina.

Violeta Castelo Szekely, one-year visiting student Oct 2016 - Sept 2017 from the University of Lausanne, funded by the NCCR Doctoral Mobility grant.

Pablo Izquierdo Garrudo, PhD rotation student in spring 2017 as part of the Wellcome Trust UCL neuroscience PhD programme.

Katja Egli, Research assistant since October 2016, works mainly with Martina and Flora.

Liam Kempthorne, PhD rotation student in spring 2018, UCL Wolfson programme.

Michael Palo, summer student from University of Madison, July-August 2018, now PhD student at Stanford.

Jan Brancewicz, summer student from Warsaw University, July-August 2018.

Edwin Jarratt Barnham, summer student from University of Cambridge, July-August 2019

Adam Sheriff, summer student from King’s College London, July-August 2019

Hallie Hanson, summer student from University of Wisconsin-Madison, July-August 2019

Emma Groblewski, summer student from University of Wisconsin-Madison, July-August 2019

Federica Capraro, MSc student and then research assisitant during January 2018 - August 2019. Now a LIDo PhD student in London.

Christoph Sadee, Research assistant Oct 2016 - Nov 2018, working on iCLIP optimisation and developing a new product. Continued to the PhD programme at Stanford.

Mariša Cvitanič, MSc student during July 2019-March 2020, worked with Miha Modic on RNA regulation in stem cells.

Yiling Li, MRes student during October 2019 - September 2020, working with Martina on TDP-43 protein, then continued to PhD studies in Magdalena Gotz's lab at the Ludwig Maximilian University of Munich.

Velentza-Almpani Angeliki, MSc student during Jan-Sept 2020 as part of a collaborative project with Louise Walport lab.


Jernej Ule Laboratory 2019-2020 

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