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London Lab

 
 
 
 
 
 
 
 

Jernej Ule, 'Jernej' is pronounced as Yernay. I obtained my BSc in Molecular Biology from University of Ljubljana, Slovenia, in 1999, and PhD and short postdoc with Bob Darnell at the Rockefeller University, New York, during 2000-2006. I started my research group at the MRC Laboratory of Molecular Biology in Cambridge in July 2006, in April 2013, we moved to the Queen Square UCL Institute of Neurology in London, and in August 2016 we were seconded to The Francis Crick Institute. In 2020, I started a satellite team at the Institute of Chemistry in Ljubljana funded by ERC advanced grant. I am an EMBO fellow and member of London RNA club, I do plenty of reviewing, I served on WT grant reviewing board and EMBO conference reviewing committee, and regularly review ERC and other grants. In April 2022, I will take the position of UK DRI Centre Director at King's College London, where the lab will gradually relocate, with a small satellite team remaining in the Crick until September 2024.

Martina Hallegger, Postdoc since October 2014 (MNDA non-clinical fellow in 2016-19). Studies ribonucleoprotein complexes in motor neuron disease.

Cristina Militti, Postdoc since October 2014 (EMBO postdoctoral fellow in 2015-16). Studies mRNA structures and their role in RNP assembly and function.

Flora Lee, PhD student 2016-2019 (Wellcome Trust UCL neuroscience programme), now a postdoc studying the neuronal functions of mRNA structures.

Julian Zagalak, Postdoc since January 2016 (funded by SNF fellowship in 2016-17). Studies combinatorial control of pre-mRNA processing.

Rupert Faraway, PhD student 2017-2020 (UCL MRC LIfe and Biomedical Science DTP PhD), now a postdoc studying the assembly of RNP condensates.

Patrick Toolan-Kerr, PhD student 2017-2020 (UCL Wolfson PhD), now a postdoc studying the effects of RNA methylation on RNP assembly.

Miha Modic, Postdoc since Dec 2017 (Henry Wellcome postdoctoral fellow), studies the functions of RNPs in stem cell differentiation.

Wei Jia Zhang, PhD student since 2018, (UCL Wolfson PhD programme), studies RNP dynamics in motor neurons and in ALS.

Oscar Wilkins, PhD student since Oct 2019 (Wellcome Trust UCL neuroscience PhD). Studies translational control by neuronal RNA binding proteins.

Llywelyn Griffith, joint AstraZeneca/Crick postdoc since Oct 2019, studies treatments targeting aberrant splicing in cancer.

Joyita Mukherjee, Postdoc since Feb 2020 (EMBO postdoctoral fellowship in 2021-23). Studies the dynamics of neuronal RNP condensates.

Hanzhong Bai, PhD student since Oct 2020 (LIDO programme and Boehringer Ingelheim fellowship). Studies RNA-RNA contacts in neurons.

Neve Costello Heaven, PhD student since Oct 2021 (UCL Wolfson-Eisai programme), studies the role of RNA condensates in neurodegeneration.

Holly Digby, Research assistant since February 2020, works mainly with Rupert.

Charlotte Capitanchik, PhD student working between Nick Luscombe and Ule labs since Oct 2017 on computational analyses of RNP assembly principles.

Ira A. Iosub, Postdoc working between Nick Luscombe and Ule labs since 2020 on computational studies of RNA structures.

Marc Jones, Postdoc working between Nick Luscombe and Ule labs since 2020 on computational RNA biology.

Karen Davey, Research assistant since 2022, works on RNA biochemistry and cell biology.

Jure Rebselj, visiting summer student in 2022, focusing on computational biology.

 
 
 
 
 
 
 
 

Ljubljana Lab

Aniela Skrzypczyk, postdoc since April 2022, studies mechanisms of RNA condensates in neuronal differentiation.

Klara Kuret, MSc student since November 2019 and started PhD in 2020, works on computational studies of nuclear RNP condensates.

Tajda Klobučar, PhD student since 2020, studies protein-RNA and RNA-RNA interactions that assemble nuclear RNP condensates, mentored by Miha Modic.

Urška Janjoš, Research assistant since December 2020 and PhD student since 2021, studies the functions of nuclear RNP condensates.

Anja Trupej, MSc student since April 2019, works with Tajda on RNP condensates.

Katarina Lenarčič, MSc student since July 2019, works on Staufen RNP assembly.

Žiga Vičič, Research assistant since October 2021, works on iCLIP, ribosome profiling and molecular biology.

 
 
 

Affiliated

Reem Abouward, PhD student working between Gianpietro Schiavo and Ule labs since October 2020 as part of the Wellcome Trust UCL neuroscience PhD programme. Studies the role of RNA transport in ALS.

Anob M. Chakrabarty, working between Nick Luscombe and Ule groups, PhD student 2016-2020, now postdoc working on computation of mRNA structures.

Mahmoud-Reza Sina Rafiee, Postdoctoral fellow working between Nicholas Luscombe and Ule labs, who uses proteomics to study RNPs and chromatome.

Julie Qiaojin Lin, Sir Henry Wellcome postdoctoral Fellow affiliated to the groups of Giovanna Malucci and Clemens Kaminski, in addition to Ule lab

Perlina Desai, UCL-Birkbeck DTP programme PhD student working jointly between Lorena Arancibia and Ule labs since October 2021.

Maria Pisliakova, Visiting student during July 2021-April 2022, works with Oscar

Grega Gimpelj, PhD student at Medical Faculty in Ljubljana, performs part of his PhD in the Ljubljana lab.

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Past Lab Members

James Tollervey, PhD student during October 2006 - April 2010, then postdoc till December 2010. Worked on regulation alternative splicing in age-related neurologic disorders. Now scientist at Aelan Cell Technologies, San Francisco.

Zhen Wang, PhD student during October 2007 - September 2010, then postdoc till September 2011. Studied how TIA proteins regulate RNA splicing and 3' end processing. Now senior scientist at Depixius, Paris.

Melis Kayikci, PhD student during October 2008 - September 2011. Studied the positional principles, or 'RNA maps', which guide the regulatory activity of RNA-binding proteins. Now bioinformatician at Genomics England.

Michael Briese, postdoc during December 2007 - March 2012. Studied how CELF4 protein regulates translation in mouse brain. Now postdoctoral fellow at University of Wurzburg.

Nicholas McGlincy, joint postdoc with the group of Michael Hastings during November 2008 – August 2012. Studied the role of alternative splicing in circadian rhythms. Now postdoc at the University of California, Berkley.

Julian König, postdoc suring November 2008 - October 2013. Studied the function of hnRNP C protein in the regulation of alternative splicing. Was funded by HFSP Postdoctoral Fellowship. Now group leader at the Institute of Molecular Biology in Mainz.

Yoichiro Sugimoto, PhD student during October 2010 - July 2014, and then postdoc during May-September 2016. Studied the function of in vivo RNA structures. His PhD was funded by the Nakajima Foundation Scholarship.

Chris Sibley, postdoc during August 2011-October 2015. Studied intronic splicing regulatory elements in neuronal genes. Now group leader at the Edinburgh University.

Jan Attig, PhD student during October 2011-April 2015, then postdoc till September 2015. Studies the coordinated control of mRNA life cycle. Was funded by Boehringer Ingelheim Scholarship. Now senior scientist at Roche, Basel.

Ina Huppertz, PhD student during October 2012-September 2015. Studies the regulation of pre-mRNA processing. Was funded by Marie Curie International Training Network. Now postdoc at EMBL.

Claire Hall, PhD student during Sept 2013 - Sept 2016. Studied RNA regulatory networks in motor neuron disease, and was funded by UCL Grand Challenge programme. Now at medical school.

Nejc Haberman, PhD student during 2013 - 2017 on computation of protein-RNA interactions. Now postdoc at MRC CSC in London.

Lilach Soreq, Postdoctoral fellow during August 2013 - November 2016, studied gene expression in the aging brain.

Warren Emmett, Postdoctoral fellow during March 2016 - February 2018. Coordinated computational studies of non-canonical splicing. Now Bioinformatics Analyst at Inivata Limited in Cambridge, UK.

Igor Ruiz de los Mozos, Postdoctoral fellow from Nov 2014-Sept 2019, studying the network mechanisms of RNA regulation, now senior bioinformatician at Spain genomics institute.

Andrea Elser, PhD student during 2016-2019 as part of the BBSRC LIDo Doctoral Training Programme. Studied the function of recursive splice sites in neurons.

Lorea Blazquez, postdoc during 2014-2018, studied regulation of recursive splicing (initially funded by Marie Skłodowska-Curie postdoctoral fellowship), and since 2018, co-supervises a Crick-LifeArc translational project. In August 2020, Lorea started her own research group at Biodonostia Health Research Institute.

Paulo Gameiro, Postdoctoral researcher 2016-2021 (Marie Skłodowska-Curie fellowship 2016-18). Studied the metabolic control of protein-RNA interactions. Since 2022, group leader at University of Coimbra, Portugal.

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Past Lab Members (<3 years)

Iris Kramberger, visiting student during August-September 2010. Now a PhD student in Oxford.

Matteo Cereda, a visiting student for 9 months in 2010 and 2011, working on a computational approach to define RNA splicing maps. Now a group leader at IIGM, Turin.

Dalia Daujotyte, short-term postdoc for five months in 2010 to study Staufen 2 protein using iCLIP. Now Chief Commercial Officer at the Lexogen company in Vienna.

Tina Lence, visiting student during March-August 2011. Now postdoc at IMB Mainz.

Josh Witten, short-term postdoc during January 2010 – June 2012. Now runs The Finch & Pea Group, Ltd - a life sciences and communication consulting firm.

Katherine Godin, short-term postdoc during October 2011 - September 2012. Now NMR Senior Scientist at Beryllium

Deepak Barnabas, 3-month visiting student November 2012 - January 2013.

Peter Juvan, visiting scientist December 2012 - February 2013.

Mojca Tajnik, visiting student, staying from March 2011 - March 2012, and March 2013-June 2013. Mojca was funded by EMBO Short-term scholarship.

Laura Easton, research assistant during October 2011 - March 2013.

Andrea D'Ambrogio, postdoc during January 2013-August 2014. Now Senior Scientist at Horizon Discovery.

Rubika Balendra, PhD rotation student in 2015, funded by UCL Wolfson programme.

Liza Malong, PhD rotation student during March-May 2015 as part of the neuroscience PhD programme.

Aarti Singh, MSc student during March-September 2014, then research assistant during October 2014-September 2015. Now PhD student at UCL.

Alexandra Zirra, MSc student during March-September 2014, then research assistant during October 2014-September 2015. Now a PhD student at KCL.

Rehan Hussain, MSc student during March-September 2016. Worked with Cristina Militti.

Isabel Weisheit, visiting student from Ludwig Maximilans University of Munich, visited from June-November 2016 to work with Martina Halleger.

Gregor Rot visited our group and collaborated on bioinformatic projects to study the regulation of 3' end processing .

Frederique Rau, Postdoctoral fellow with Rickie Patani, who was hosted in our lab for a year.

Eleni Anastasakou, Lena was an MRes student during Oct 2016 - Sept 2017. Studied the long-range mRNA structures, together with Cristina.

Violeta Castelo Szekely, one-year visiting student Oct 2016 - Sept 2017 from the University of Lausanne, funded by the NCCR Doctoral Mobility grant.

Pablo Izquierdo Garrudo, PhD rotation student in spring 2017 as part of the Wellcome Trust UCL neuroscience PhD programme.

Katja Egli, Research assistant since October 2016, works mainly with Martina and Flora.

Liam Kempthorne, PhD rotation student in spring 2018, UCL Wolfson programme.

Michael Palo, summer student from University of Madison, July-August 2018, now PhD student at Stanford.

Jan Brancewicz, summer student from Warsaw University, July-August 2018.

Edwin Jarratt Barnham, summer student from University of Cambridge, July-August 2019

Adam Sheriff, summer student from King’s College London, July-August 2019

Hallie Hanson, summer student from University of Wisconsin-Madison, July-August 2019

Emma Groblewski, summer student from University of Wisconsin-Madison, July-August 2019

Federica Capraro, MSc student and then research assisitant during January 2018 - August 2019. Now a LIDo PhD student in London.

Christoph Sadee, Research assistant Oct 2016 - Nov 2018, working on iCLIP optimisation and developing a new product. Continued to the PhD programme at Stanford.

Mariša Cvitanič, MSc student during July 2019-March 2020, worked with Miha Modic on RNA regulation in stem cells.

Yiling Li, MRes student during October 2019 - September 2020, working with Martina on TDP-43 protein, then continued to PhD studies in Magdalena Gotz's lab at the Ludwig Maximilian University of Munich.

Velentza-Almpani Angeliki, MSc student during Jan-Sept 2020 as part of a collaborative project with Louise Walport lab.

Aram Amalietti, Data Analyst during February 2019 - July 2021, software development and computational analyses of CLIP data.

Miha Sovrovič, Research assistant during December 2020 - September 2021, worked on ribosome profiling and genome editing.

Nina Lenaršič, Summer student in 2021, worked with Urška Janjoš.

Špela Barbič, Summer student in 2021, worked with Miha Milek.

Parth Patel, MSc student in Oct 2018-Sept 2019, and research assistant during Jan-Sept 2020 working on splicing modulation.

Lea Knez, Erasmus visiting student during Sept-Nov 2021, worked with Rupert Faraway

Zuzana Koskova, Erasmus visiting student during Sept-Dec 2021, worked with Martina Hallegger.

Stacy Steinberg, was Marie-Currie International postdoctoral fellow working between Su Guo lab at UCSF and Ule lab on the protein Rbm12a.

Miha Milek, Senior postdoctoral researcher during Jan 2020 - Mar 2022, who helped establish the Ljubljana team and worked on Staufen RNP assembly.

Nuša Avguštinčič, BSc student visiting Ljubljana team in winter 2022.